Yearly Archives: 2024


X chromosome loss in females linked to leukemia and autoimmune risk

Senior computational biologist and co-first author, Giulio Genovese, recently published “Genetic drivers and cellular selection of female mosaic X chromosome loss” in Nature. In this study, we explored the genetic causes and health implications of mosaic loss of the X chromosome (mLOX) in females. We analyzed data from over 880,000 […]

Colorful mosaic art of a person's silhouette, composed of small blue, red, yellow, and orange tiles with some tiles breaking away from the mosaic.

A new study of aging and schizophrenia reveals synchronized gene expression in astrocytes and neurons.

Postdoctoral researcher, Emi Ling, published her work on “A concerted neuron-astrocyte program declines in ageing and schizophrenia” in Nature. Ling et al. analyzed the prefrontal cortex of 191 human donors by single-nucleus RNA-seq of postmortem brain tissue samples pooled together in “villages.” We found a striking relationship between cortical neuron […]

Schematic of a neuron and astrocyte

Khalid Shakir featured in #WhyIScience Q&A Broad news story

In a recent #WhyIScience Q&A Broad news story, principal software engineer, Khalid Shakir, shares his journey from tinkering with spare equipment in his parents’ high school classrooms to pioneering large-scale computational tools, his passion for emerging technologies like AI, and the invaluable role of affinity groups like A4C in fostering […]

Khalid Shakir sitting on chair in office building